Into the Night (1985)

After discovering that his wife is cheating on him, an insomniac aerospace engineer (Jeff Goldblum) accidentally meets, and tries to help, a beautiful model (Michelle Pfeiffer) on the run from some extremely dangerous people. The cult comedy classic is directed by John Landis, who also appears in the film, alongside an ensemble cast of Hollywood heavyweights such as Dan Aykroyd, director David Cronenberg, Paul Mazursky, and David Bowie, who steals the movie with his turn as a vicious, cool and hilarious killer.